Objectives: Over the past two decades, a large interest in cardiac marker elevations has developed\nin endurance sports events. The intense effort is not without risk. We aimed to see if the relatively\ncardiospecific biomarkers could show the damage on cardiac muscle cells. Methods: Fourteen\ncyclists were recruited for an international race (177 km). We studied different cardiac biomarkers,\nrenal function markers and blood cytology. The subjects were submitted to three blood test:\none before (T0), one just after (T1) and the last one 3 hours after the race (T3). Results: Blood cytology\nmarkers, namely erythrocytes, hemoglobin, hematocrit, and average hemoglobin concentration,\nwere found to evolve in a similar way. Renal function markers, such as creatinin, cystatin C\nand uric acid, showed a post effort increase that might be related to renal blood flow depletion\nduring exercise. Cardiac and muscular markers were all increased at T1. Conclusions: Physiological\nstress induced by an international cycling race certainly has consequences on cardiac muscle\ncells. Fortunately, those blood concentration variations are more representative of a transitional\nstate, due to an imbalance created by an intense aerobic effort maintained during several hours,\nrather than an irreversible injury.
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